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Tapentadol is a centrally acting opioid analgesic medication used primarily for the management of moderate to severe pain. It works by binding to mu-opioid receptors in the central nervous system, which helps to alleviate pain. Tapentadol is prescribed for the treatment of acute pain severe enough to require opioid analgesia and for the management of chronic pain when other treatments are inadequate. It may be used for conditions such as musculoskeletal pain, neuropathic pain, and postoperative pain. Tapentadol works through dual mechanisms. It acts as both a mu-opioid receptor agonist and as a norepinephrine reuptake inhibitor (NRI).
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