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Modafinil is a medication primarily used to treat excessive daytime sleepiness associated with narcolepsy, obstructive sleep apnea, and shift work sleep disorder. It is also sometimes prescribed off-label to treat other conditions, such as attention deficit hyperactivity disorder (ADHD), depression, and fatigue associated with conditions like multiple sclerosis. The exact mechanism of modafinil is not fully understood, but it is believed to work by increasing the levels of certain neurotransmitters in the brain, including dopamine, norepinephrine, and histamine. These neurotransmitters play a role in wakefulness, attention, and cognitive function. Modafinil is primarily indicated for the treatment of excessive daytime sleepiness associated with narcolepsy, obstructive sleep apnea, and shift work sleep disorder.

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