Tasked with finding and destroying the fragments left from the shattered Worldstone created by fan-favorite NPC Deckard Cain before they are used to trigger a cataclysmic event, players have to explore the world in order to deal with the consequences of Tyrael's action. The shards of the Worldstone have also attracted other ancient evils such as Skarn, the Lord of buy cheap Diablo IV Gold Damnation who wants to gather the fragments and utilize their power to oppress the human race.
Due to Diablo 4's status as an epoch-making sequel to Diablo 2 and a prequel to Diablo 3. it occupies an interesting spot in the chronology. As an MMORPG it is likely to see regular updates and fresh content across several years, as well as new expansions to the storyline that will eventually take in the entire period from Diablo 2 in 1265 and Diablo 3 in 1285.
The game is not like the other self-contained ones, Diablo 4's story is possible to be ongoing in the near future, with Blizzard offering even more extensive content updates in the near future. The sequence of events in Diablo 3 and its expansions are likely to be completed, however the game's creator has a fair amount of time between entries to experiment with if it wants to extend the story of Diablo 4.
It may be able to combine the both games by having events in the MMORPG taking place simultaneously to Diablo 3's gameplay. This could get a little convoluted, however, and could require some slight rethinking to allow it to work. Diablo 3 represented some major plot elements for the series such as the Archangel Tyrael's deportation from buy Diablo IV Gold the High Heavens, the search for the Black Soulstone, and the temporary resurrection of Diablo prior to his being defeated by the Nephalem.